The report Professional Social Work Response to COVID-19 Affected Families in India: Facilitating Services and Building Awareness during the Second Wave, is the outcome of a nationwide online survey carried out between July and September 2021 to capture the professional social work’s response to the second wave of the COVID-19 pandemic in India. It comprises of the analysis of responses received from Depts./schools of social work, Civil society organisations (CSOs)/units of CSOs or government organisations headed by professional social workers, and individual social workers representing all the states and the Union Territories. Findings revealed the widespread role social work organisations and individual social workers played in supporting the affected families and communities during the second wave. The Report highlights the strengths of social work profession in helping and empowering vulnerable and marginalised individuals, groups and communities in the society.